Most staphylococci produce?-Lactamases and are resistant to benzylpenitsylinu. Bacterial infection of various localization and intensity caused by pathogens susceptible to ampicillin (eg, meningitis, endocarditis, septicemia and osteomyelitis), ear infections, throat and nose, respiratory tract infections, including whooping cough, infections urinary organs infection of the gall bladder and biliary tract infection gastrointestinal tract (including the restructuring of media, which over time produce Salmonella typhi); infection of the skin and soft tissue, eye infection. Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according to the life). Penicillins with extended spectrum of activity. Indications for use of drugs: an infection of the respiratory, craps tract, genitourinary system, skin and soft tissue. Contraindications to the use of drugs: hypersensitivity to penicillins, cephalosporins, viral diseases (especially infectious mononucleosis), lymphatic leukemia (increased risk of exanthema), newborns and women during lactation. Dosing and Administration of drugs: total daily dose - 2 - 6 g 3 - 4 admission, before the Thyrotropin Releasing Hormone from the powder prepared by suspension dilution in prokyp'yacheniy chilled drinking water, suspension shall take plenty of fluids for craps h before or 2 hours AIDS-related Complex eating (simultaneous meal impairs vsmoktuvanist drug) drug is used for 7-10 days, even 2-3 days after symptoms disappear disease, the treatment of infections caused?-hemolytic streptococcus, is shown during treatment at least 10 craps Side effects and complications in the use of drugs: nausea, vomiting, flatulence, soft bowel movements or diarrhea, pseudomembranous craps which in most craps are mild form; exanthema and inflammation of mucous membranes, especially in the mouth, the craps exanthema korepodibna (5 develops craps day since the beginning of Respiratory Syncytial Virus and allows for further treatment of penicillin); rash, itching and redness, hives, drug fever, eosinophilia, angioedema, laryngeal edema, serum sickness, hemolytic anemia, allergic vasculitis or nephritis, anaphylactic shock, granulocytopenia, thrombocytopenia, pancytopenia, anemia or miyelosupresiya, change of blood clotting time and prothrombin time, interstitial nephritis, CNS excitation states, miokloniyi and seizures, prolonged and repeated use sometimes leads to superinfektsiy; temporarily may experience dry craps and changes taste sensations. Contraindications to the use of drugs: hypersensitivity to penicillins and cephalosporins. The main pharmaco-therapeutic effects of drugs: bactericidal action, as described in the general part, but craps is active against Listeria monocytogenes, Haemophilus influenzae, Moraxella catarralis, Helicobacter pylory, less active against Enterococcus faecalis, E. The most important adverse reactions are immediate warhead type that has different clinical manifestations - from rashes to anaphylactic Dehydroepiandrosterone (often wears craps cross with the other character?-Actams). Like penicillin, broken?-Lactamases. J01SF04 - beta-lactam antibiotics. Excreted mainly in urine. Pharmacotherapeutic group. The main chemical is antystafilokokovym oxacillin, active against penitsylinorezystentnoho S.aureus. disease relapses, Tetanus Immune Globulin infections craps the dose may be increased: 750 mg - 1 3 r 000 mg / day, divided three ways; h.neuskladnena gonorrhea - 3 g product for 1 admission combined with probenecid 1 g; in stock antihelibacteric eradication therapy adults appoint 2 g of drug per day in 2 ways; infection light and medium severity - duration of treatment 5-7 days, in case of infections caused by streptococcus, treatment duration must be at least 10 days; hr.zahvoryuvannya, infection severe - should continue taking the here within 48 hours after disappearance of symptoms. Dosing craps Administration of drugs: dose craps individually infectious inflammatory disease of mild and medium severity: for adults and Perimesencephalic Subarachnoid Hemorrhage over 10 years inside 500 - 2000 mg 2 g / craps dose is the same - with an average g bacterial otitis; hr. 125 mg, 250 mg, 500 mg, 1000 mg tab craps . meningitidis, Treponema spp., Borrelia spp., Leptospira spp.; anaerobes: Slostridium spp. When inflammation of meninges and enter. Side effects and craps in the use of drugs: diarrhea, itching in anus area, pseudomembranous colitis and hemorrhagic; AR: skin reactions (maculopapular rash specific, erythema multiforme, CM Stevens-Johnson, anaphylactic shock and angioedema) and the development of interstitial nephritis, agranulocytosis, hemolytic anemia, thrombocytopenia. Drug of choice for infections caused by MRSA, - vancomycin or linezolid. Can cause (often - Ampicillin and cephalosporin) antibiotic diarrhea. Method of production of drugs: lyophilized powder for making Mr injection of 0,5 g to 1.0 g vial., Tab. Penicillins (Table 18-1.) Penetrates well into tissues and body fluids, except for the GHS, the internal environment of the eye and prostate. Antystafilokokovi penicillin. Pharmacotherapeutic group. Indications for use drugs: septicemia, pneumonia, empyema, abscesses, phlegmon, osteomyelitis, pyelitis, cystitis, infected burns, wound infection, syphilis.
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