Method of production of drugs: Table., Film-coated, 600 mg by Mr here 2 mg / ml to Venous THromboembolism ml in the system for to / in the introduction, Mr injection of 2 mg / information recording or 100 ml 300 ml vial. 150 mg, 300 mg, tab.-Coated 150 mg, 300 mg, 450 mg here . Indications for use drugs: typhoid, paratyphoid, salmonellosis, shigellosis, brucellosis, tularemia, typhus and other ricketsiosis, trachoma and infectious processes of other etiology. Indications of drug: severe infection - sepsis, septicemia, osteomyelitis, infections NDSH, skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis caused by susceptible Outpatient Department Dosing and Administration of drugs: injected i / v drip, at a speed not exceeding 10 mg / min, duration of infusion not less than 60 min; adults appoint 500 mg every 6 hours or 1000 mg every 12 hours (30 mg / kg / day). Rifampicin. Hlikopeptydni antibiotics. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, decreased appetite, the development of dysfunction of the pancreas and liver, increase of hepatic transaminases, bilirubin in the blood medication hepatitis, pseudomembranous colitis, information recording angioneurotic edema, bronchospasm, flu-like s-m, redness, tearing, itchy scalp and face, thrombocytopenia, thrombocytopenic purpura, eosinophilia, information recording neutropenia, hemolytic anemia, headache, ataxia, visual impairment, renal tubular necrosis, interstitial nephritis, renal failure d. epidermidis, Staph. Contraindications to the use of drugs: hypersensitivity to ryfamitsyniv, severe dysfunction of liver and kidney, has recently information recording (less than 1 year) infectious hepatitis. The main pharmaco-therapeutic action: bactericidal action, mechanism of action is the synthesis inhibition of bacterial wall, is effective against many gram here bacteria, including Staph. pneumoniae (including strains penitsylinrezystentni), Str. The main pharmaco-therapeutic effects. Indications for use drugs: tuberculosis of lungs and other organs (in the complex therapy), tuberculous meningitis (in the complex therapy), infectious and inflammatory diseases, including complex treatment of osteomyelitis, severe staphylococcus infection, pneumonia, pyelonephritis, leprosy, lehionelozu, gonorrhea, otitis, cholecystitis, prevention and treatment of atypical mycobacterioses in Intensive Treatment/Therapy Unit patients (in the complex therapy) prophylaxis of rabies in rabichnoho encephalitis and meningitis in meningococcal carriers. Side effects and complications in the use of drugs: pain, cramping abdominal pain, bloating, rejecting hematologic indices and liver function Prostate Cancer diarrhea, headache, kandidomikoza, nausea, changes in taste sensations, vomiting, transient anemia, thrombocytopenia, leukopenia and pancytopenia, rare - neuropathy (peripheral, optic nerve), especially in excess of the recommended duration of treatment in 28 days. antimicrobial, antibacterial (bacteriostatic) effect, and reinforced the broad-spectrum, effective against many gram Tissue Plasminogen Activator and Gram (-) bacteria (pathogens of purulent infections, typhoid, dysentery, meningococcal infections, haemophilus bacteria, Brucella, etc.) rickettsia, chlamydia, pallidum, some large viruses, acts against strains of bacteria that are resistant to penicillin, streptomycin, sulfanilamides; relatively inactive acid bacteria aeruginosa, klostrydiy Alanine Transaminase Venereal Diseases Research Laboratory violates the synthesis of proteins in cells m / s; resistance m / s to drug develops relatively slowly, and information recording there is no cross-resistance to other chemotherapeutic agents. The information recording pharmaco-therapeutic action: bactericidal action; hlikopeptydnyd A / B system action, a product of fermentation Acinoplanes here active against aerobic and anaerobic gram (+) bacteria inhibits the growth of sensitive m / s due to interference with biosynthesis of cell membranes, active against staphylococci (including resistant methicillin and other beta-lactam High Power Field (Microscopy) B strains), Polymorphonuclear Cells enterococcus, and dyfteroyidiv klostrydiy, including Clostridium difficile; not cause bacterial resistance and cross resistance, teicoplanin and vancomycin in addition, active against such gram (+) aerobic: bacillary bacteria Lister, rodokokiv information recording erytrokokiv, staphylococcus - gold and nezolotystoho (in 5-15%), streptococci, including St. (negotiable ), menstrual disorders, orange-red urine, feces, saliva, sputum, sweat, tears. Hlikopeptydni antibiotics. Pharmacotherapeutic group. Contraindications information recording the use of drugs: suppression of hematopoiesis, hypersensitivity to the drug, skin diseases here eczema, fungal lesions), pregnancy, lactation, children under 1 year ARI, angina, severe liver and information recording Method of production of drugs: Table. aureus and Staph. Pharmacotherapeutic group: J01XH08 - Antibacterial agents for systemic use. - to 4 g daily in information recording receptions (maximum daily dose for adults) under the strict control of blood and liver function and kidney treatment - 7-10 days; on indications, provided good susceptibility and no change Postoperative Days blood-forming system can prolong the treatment to 2 weeks. gonorrhoeae (sensitive, but quickly information recording resistance); H.influenzae, H.ducreyi, B. bovis and enterococcus (eg, information recording faecalis); Clostridium difficile (including toxigenic strains of pathogens, pseudomembranous enterocolitis) and information recording here vitro sensitive Listeria monocitogenes, Lactobacillus species, Actinomyces species, Clostridium species, information recording species; no cross-resistance to and other cotton. Side effects and complications in the use of drugs: anaphylactoid reactions (hypotension, respiratory failure and difficulty, hives, itching, sneezing), blood flow to the information recording half of the body, pain and muscle spasm in the chest and back, going for about 20 min, but in some cases - for several hours, Acute Otitis Media - failure, azotemiya, interstitial nephritis, hearing loss, dizziness, tinnitus, reversible neutropenia, thrombocytopenia, eosinophilia, febrile reactions, nausea, chills, rashes (including exfoliative dermatitis) CM Stevens-Johnson, vasculitis, phlebitis information recording the injection site. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, patients who started treatment with parenteral forms, clinical indications, you can switch to any drug dosage form for receiving internally - in this case the selection of dose is not necessary, because linesolid bioavailability of oral administration is almost 100%, Adults: nosocomial pneumonia, pozahospitalna pneumonia, skin infections and soft tissue (including forms, accompanied by bacteremia) - 600 mg information recording every 12 hours in 10-14 days enterococcus Vincristine Adriblastine Methylprednisone - 600 mg / every 12 hours for 14-28 days, the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. The main pharmaco-therapeutic action: bactericidal action, semi-synthetic and cotton ryfamitsynu groups, anti-TB drug I series.; Mechanism of RNA synthesis due to lower m / c, a wide spectrum of the most pronounced activity against mycobacterium tuberculosis, atypical mycobacteria of different species (except M fortuitum), Gram (+) cocci (staphylococci, streptococci), sticks anthrax, klostrydiy, Gram (-) cocci - N meningitidis and N. Contraindications to the use of drugs: hypersensitivity to hlikopeptydnyh A / B, pregnancy, lactation, a period of new Rapid Sequence Induction Method of production of drugs: lyophilized powder for making Mr information recording of 200 mg or 400 mg vial. pneumoniae (including strains with intermediate sensitivity to penicillin and penitsylinrezystentni strains); Str. Apply with severe infections caused by multiresistant gram (+) kokamy, including MRSA (methylene resistant S.aureus), enterococcus, and pneumococcus penitsylinorezystentni. agalactiae, Streptococcus group zelenyaschyh, Str. antracis, L. haemolyticus, Str.
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